Haemophilus influenzae Type b Meningitis in Children, Eritrea
نویسندگان
چکیده
منابع مشابه
Haemophilus influenzae Type b Meningitis in Children, Eritrea
To the Editor: Bacterial meningitis is a major cause of death and disability in children worldwide: >1,000,000 cases and 200,000 deaths are estimated to occur each year. Neisseria meningitidis, Haemophilus influenzae type b (Hib), and Streptococcus pneumoniae are major causative agents of bacterial meningitis in children. A region in sub-Saharan Africa, extending from Ethiopia in the east to th...
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ABSTRACT Background: A polymerase chain reaction (PCR) assay with primers from "hpd" gene was compared with culture for the detection of Haemophilus influenzae type b (Hib) in CSF samples from children suspected of meningitis. Methods: 300 cerebrospinal fluid (CSF) samples from suspected meningitis cases were studied by culture (Leventhal & Chocolate Agar) and PCR. Results: The latter...
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The age-related acquisition of serum anticapsular and bactericidal antibodies to Haemophilus influenzae type b observed in rats was similar to that of humans. The antigenic source for this "natural" immunity was not identified, since neither pharyngeal infection with H. influenzae b nor enteric colonization by cross-reacting bacteria was detected. Infant rats surviving H. influenzae b bacteremi...
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The families of 126 consecutive patients with Haemophilus influenzae type B meningitis were surveyed for secondary invasive H influenzae disease among household contacts. A total of 120 of the families were contacted. In six cases no contact was possible and the medical record was reviewed. Some 555 household contacts were found; 31% (171) were under 5 years of age. A secondary case was defined...
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Detection of Haemophilus influenzae type b (HIb) antigenuria by latex agglutination has been shown to be sensitive, specific, and rapid. In children, antigenuria persisted for a mean duration of 10 days and a maximum of 18 days. Antigenuria was demonstrated in 25 of 30 patients with HIb infection but not in 62 with other types of infection. In five children, antigenuria confirmed the diagnosis ...
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 2004
ISSN: 1080-6040,1080-6059
DOI: 10.3201/eid1001.030132